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AbstractWill we, by 2050, be able to feed a rapidly growing population with healthy and sustainably grown food in a world threatened by systemic environmental crises? There are too many uncertainties for us to predict the long-term evolution of the global agri-food system, but we can explore a wide range of futures to inform policymaking and public debate on the future of food. This is typically done by creating scenarios (story lines that vividly describe what different futures could look like) and quantifying them with computer simulation models to get numerical estimates of how different aspects of the global agri-food system might evolve under different hypotheses. Among the many scenarios produced over the last twenty years, one would expect to see the future advocated by the food sovereignty movement, which claims to represent roughly two hundred million self-described "peasants" (small farmers) worldwide. This movement defends a vision of the future based on relocalized, sustainable, and just agri-food systems, self-governed through direct and participatory democratic processes. Yet, food sovereignty is conspicuously absent from quantified scenarios of global food futures. As part of the roundtable, "Ethics and the Future of the Global Food System," this essay identifies seven obstacles that undermine the creation of food sovereignty scenarios by examining two attempts at crafting such scenarios.

Recently, there have been increasing numbers of activities labeled as either quality improvement (QI) or comparative effectiveness research (CER), both of which are designed to learn what works and what does not in routine clinical care settings. These activities can create confusion for researchers, Institutional Review Board members, and other stakeholders as they try to determine which activities or components of activities constitute clinical practices and which constitute clinical research requiring ethical oversight and informed consent. We conducted a series of semi-structured focus groups with QI and CER professionals to understand their experiences and views of the ethical and regulatory challenges that exist as well as the formal or informal practices and criteria they and their institutions use to address these issues. We found that most participants have experienced challenges related to the ethical oversight of QI and CER activities, and many believe that current regulatory criteria for distinguishing clinical practice from clinical research requiring ethical oversight are confusing. Instead, many participants described other criteria that they believe are more ethically appropriate. Many also described developing formal or informal practices at their institutions to navigate which activities require ethical oversight. However, these local solutions do not completely resolve the issues caused by the blurring of clinical practice and clinical research, raising the question of whether more foundational regulatory changes are needed.

"In the "Letters from a Post-Corona Future" study, we asked participants to imagine a desirable world after the Corona crisis and their own place within it. In resulting narratives, any imagined that the future will not look like the past, but did they also imagine that their own moral orientation would change, that is, their stance towards what is a good human life, the norms and values deserving respect, and their moral behavior? To explore what we call "anticipated moral change", we focused on Generation X participants (born between 1965 and 1980) since they may be sufficiently mature to have a settled moral orientation and feel concerned by the future, yet sufficiently adaptable to envision internal change. A total of 64 letters from 11 countries were examined. We used concepts from narrative ethics and futures studies to investigate whether anticipated moral change was present in the letters, and if so, in what direction. We identified six categories of anticipated moral change, from radical moral innovation to daily behavior change. We analyzed how these changes were depicted (e.g., metaphors, modals, idiomatic expressions, narrated futures), felt, justified or evaluated. Results consider the forward-looking moral self-perception of participants in terms of daily behavior, emotions, thoughts, self-advice, norms, values, ideals, images, and dreams, thus contribudting to a better understanding of prospective moral change in times of health crisis. We further conceptualized two important categories of change: the inclusion of personal change into collective moral change and renewed moral awareness. "